Decision checklist
Thinking of Switching From Mounjaro to Wegovy? A Five-Question Checklist
A short companion to our full guide on switching from Mounjaro to Wegovy. Work through these five questions before your consultation; if your reason for switching survives them, it is probably a sound one.
1. Am I switching for results, tolerability or price?
Results: the head-to-head trial (SURMOUNT-5) found greater average weight loss with tirzepatide, so Wegovy is unlikely to deliver more. Tolerability: a fair reason; some people simply do better on one. Price: only a reason if Wegovy is cheaper at the dose you would actually maintain, from a pharmacy you would actually use.
2. Have I exhausted the options on Mounjaro?
If side effects are the issue, has your prescriber tried holding a dose for longer, dropping back a step, or timing changes? If a plateau is the issue, has dose, adherence and diet been reviewed? Our guide on when weight loss slows covers the usual causes.
3. Do I know the starting dose and what the first weeks will feel like?
There is no official conversion. Most prescribers start Wegovy at 0.5 mg or 1 mg for someone established on Mounjaro and step up every four weeks, so expect a few weeks of returning appetite and possibly some nausea while the dose builds.
4. Have I compared live total costs, not headlines?
Compare your current monthly cost at your dose, delivery included, against Wegovy at the likely maintenance dose, on Monj and iGovy. Prices for both moved a lot after September 2025 and still move month to month.
5. Who suggested it, and why?
If the idea came from you or your GP, weigh it on the answers above. If it came from a pharmacy consultation, ask what the clinical reason is. A suggestion driven by stock or price can still suit you, but you should know which it is.
Sources
- Aronne LJ et al. Tirzepatide as compared with semaglutide for the treatment of obesity (SURMOUNT-5). New England Journal of Medicine, 2025.
- Medicines and Healthcare products Regulatory Agency, via the electronic medicines compendium. Wegovy: Summary of Product Characteristics.
Monj is an independent price information service operated by Medstack Ltd. It does not sell, prescribe or supply medicines and does not give medical advice. Whether to switch is a decision for your prescriber.